Dynamic loads are determinants of peak bone mass

NICHD Conference Abstracts: Determinants of Peak Bone Mass

Peak bone mass (PBM) is has been defined as: (1) the maximum bone mass attained in adulthood; (2) the amount of bone acquired when bone gain ceases; and the BMD during the plateau that follows growth and bone mass accrual and precedes the bone loss that occurs later in adulthood. These definitions lead to different approaches for identifying PBM. Most commonly, PBM has been defined based on cro...

Childhood bone mass acquisition and peak bone mass may not be important determinants of bone mass in late adulthood.

During childhood and adolescence, bone mass acquisition occurs primarily through skeletal growth. It is widely assumed that bone mass acquisition throughout childhood is an important determinant of the risk of osteoporosis in late adulthood; bone mass is thought to resemble a bank account in which deposits persist indefinitely. However, several well-controlled clinical studies suggest that incr...

Determinants of bone mass

School of Medicine, Walailak University, Nakhon Si Thammarat

Clinical review 117: Hormonal determinants and disorders of peak bone mass in children.

Delayed puberty and peak bone mass.

The accrual of bone mass during childhood and adolescence is a major determinant of peak bone mass (PBM), and thereby of the risk of osteoporotic fractures occurring in advanced age (1). The development of noninvasive techniques, such as dual-energy X-ray absorptiometry (DXA), has made it possible to determine with precision and very low radiation exposure the pattern of bone mineral mass accum...